Search on: APOLIPOPROTEIN C-II 
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Descriptor English:   Apolipoprotein C-II 
Descriptor Spanish:   Apolipoproteína C-II 
Descriptor Portuguese:   Apolipoproteína C-II 
Tree Number:   D10.532.091.400.750
D12.776.070.400.400.750
D12.776.521.120.400.750
Definition English:   A 9-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS. It contains a cofactor for LIPOPROTEIN LIPASE and activates several triacylglycerol lipases. The association of Apo C-II with plasma CHYLOMICRONS; VLDL, and HIGH-DENSITY LIPOPROTEINS is reversible and changes rapidly as a function of triglyceride metabolism. Clinically, Apo C-II deficiency is similar to lipoprotein lipase deficiency (HYPERLIPOPROTEINEMIA TYPE I) and is therefore called hyperlipoproteinemia type IB. 
See Related English:   Hyperlipoproteinemia Type I
 
History Note English:   2007; use APOLIPOPROTEIN C-II (NM) 1978-2006 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   52263 
Unique Identifier:   D053304 

Occurrence in VHL:
 

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